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MPX Series (buit-in laser)

Multimodal Multiphoton

Free moving 360-frontend (scanhead), permanently aligned femtosecond fiber laser, built-in PMTs (up to 4 in epi and transmission), piezo objective scanner, motorized 3-position turret.
Translation: 3 – 5 axis stages allow 360-frontend rotation and translation in 3D
Fully integrated, air cooled, compact, flexible controller unit including build- in femtosecond laser, cw laser and high performance PC. High resolution display, software, mouse and keyboard included, non-detachable umbilical between controller and 360-frontend (2 m)


The MPX-series multiphoton multimodal imaging platform is highly modular, offering two standard models that can be customized with options and accessories.

Users have the flexibility to design a multiphoton microscope that suits their specific needs and budget.

The scanhead can be easily configured in various positions, and the modular design allows for future upgrades and the addition of extra features on the same platform.

  • Offers multiple imaging modes
  • Built-in laser
  • Dual-output tunable wavelength and low-noise 1030 nm fixed wavelength
  • Up to 4 ultra sensitive GaAsP PMTs with low dark count rate in epi or transmisson
  • Fully flexible 360° scanhead for inverted, upright or oblique angle imaging
  • Integrated workspace illumination
  • Large 2“ detection optics
  • Easy mode switching via software
  • User-friendly, compact and air-cooled




Multimodal microscope with one integrated fixed wavelength femtosecond laser. Fixed wavelength at 1030 nm.


Multimodal microscope with integrated fixed and tunable wavelength femtosecond laser. Fixed wavelength at 1030 nm, tunable wavelength in the range of 765 to 940 nm.
Laser source: built-in femtosecond lasers
Single-wavelength: 1030nm. All parameters @ sample: 100 MHz (40 MHz**), >600 mW, <140 fs @sample
Second wavelength: 765 - 940 nm (tunable in range) 100 MHz, >200 mW / output, <140 fs @sample


(I) Modality: multiphoton fluorescence imaging

Motorized laser power control:
0.5 % - 100 %
Scan path
Galvo-galvo or resonant-galvo-galvo* scanner
Scan speed (galvo-galvo / resonant-galvo-galvo)
4.6 fps at 512 x 512 pixels / 0.3 fps at 2048 x 2048 pixels / Pixel dwell time: 0.8 to 32 µs / 30 fps at 512 x 512 pixels (8 kHz resonant galvo CRS8K) / Pixel dwell time: 44 ns
Field of view (FOV)
20 mm diagonal square (max) at the intermediate image plane
Beam diameter @ objective back aperture plane
20 mm
Point spread function
Depending on installed objective
Scan zoom (digitally via ScanImage)
1x to 99x
Scan size
Up to 2048 x 2048 pixels (Both bi- and unidirectional)

(II) Modality: widefield fluorescence imaging

Excitation lightsource for epi-fluoresence widefield imaging
White-light LED or up to 9 channel solid-state based illumination
Filter set
Dichroic and emission filter sets individually optimized for 5+4 channels included. Both filter sets manually changeable
Widefield fluorescence camera
sCMOS monochrome, 6.5 µm pixel size, readout noise 2.1 med e-, quantum efficiency up to 80 %, spectral range 370 nm - 1100 nm, dark current (typ.) 15 e- / pixel / s


ScanImage Basic or Premium 2023 or higher
Laser scanning
System monitoring & modality change
MS WindowsTM 10 64-bitProfessional
PC operating system
ImageJ (Fiji)
Image post-processing
Scanimage and house-written acquisition scripts


Non-detachable umbilical between controller and scanhead, >2.0 m length
Stand-alone controller with handles and wheels
No chiller, fully aircooled
Single phase, 85 - 240 VAC, 10 A max (max 800 W total power consumption).
Size scanhead
50 cm x 40 cm x 15 cm (WxHxD)
Weight controller
30 kg.
Weight scanhead
20 kg.
Built-in PC hardware
ATX gaming board, AMD Ryzen 9 3900X, 64 GB RAM DDR4, 500 GB SSD NVMe, 4 TB HDD, Quadro RTX 4000 GPU
Storage temperature
15°C to +50°C
Operating enviroment
18°C - 27°C. Extended operating conditions available
10% - 90% (non condensing)


3-positions, motorized & software controlled
Nikon 16x N16XLWD-PF objective included. System requires infinity corrected objectives
Turret threading
M32 x 0.75

Multiphoton signal detection

Detection (up to 4 PMTs)
Non-descanned fluorescence excitation detection, up to 4 PMTs, HDDs, SiPMs or SPADs in epi or transmission.
Collection optics
Extra-large highly efficient 2“ achromatically compensa- ted detection optics, collection of fluorescence photons within +/- 12° from objective back aperture

Download full specification


Broad range of applications

  • 2D/3D/4D imaging
  • In-vitro & in-vivo
  • Whole slide imaging
  • Label-free & IHC/ICC
  • Non-destructive
  • Deep tissue imaging
  • Pathology & Cancer

  • Neuroscience

  • Optogenetics

  • Tissue Engineering & Bioprinting

  • Spheroids/Organoids


Improved research methods, new discoveries – the broad field of life science is changing constantly.


The broad field of clinical diagnostics and research is highly complex and poses many challenges in microscopy.


Ready to go out of the box

There is no need for a technician to screw things together at the customer site. Our microscopes ship fully assembled and ready to use right out of the box.

Plug & Play

Our microscopes are easy to setup and easy to use. They are designed fundamentally to be used by anyone in any location.

Multimodality at its best

Experience the convenience and power of multimodal imaging in a flexible, upgradable, modular package.

No optical table

There is no need for an optical table. Our microscopes are designed to be used anywhere, by anyone.

Energy efficient

No excessive heat and quiet operation that helps save energy and reduces the cost of system maintenance.

Easy to transport

Our system is easy to transport, making it the ideal system for a flexible working space and sharing it with other groups.

Always aligned

The lasers and optics are permanently aligned and ready to use so you can spend less time getting things set up and running. More time for imaging.

No water cooling

Our air cooled system is not only energy efficient but also ready within a few minutes (short laser warm up time) and can be set up in almost any indoor working space.

Free-moving scanhead

With our unique free-moving scan head, users can image samples of varying size from every angle.


Our software allows for the collection of more reliable data in less time. Our Windows 10 scripts are customized to automate workflows and integrate external image analysis programmes.

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